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KMID : 0352120200350010022
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Journal of Kyung Hee University
2020 Volume.35 No. 1 p.22 ~ p.24
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Anesthesia in Patients with Acute Intermittent Porphyria: A Case Report
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Kim Yun-Jong
You Ann-Hee
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Abstract
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Acute intermittent porphyria (AIP) is a rare meta-bolic disorder caused by deficiency of porphobilinogen deaminase. Acute attack of AIP may be precipitated by many factors during surgery including fasting, dehyd-ration, stress, infection, and drugs. The majority of acute attacks manifest as fluctuating blood pressure, tachycardia, electrolyte disturbances, and urinary retention. Even, bradycardia and sudden cardiac arrest can be occured. Therefore, selection and documentation of appropriate medications should be done in advance to prevent any perioperative crises. We report the safe use of propofol, rocuronium and sevoflurane in a patient affected with AIP.
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KEYWORD
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Porphyria, Acute Intermittent, Porphy-rinogens, safe anesthesia
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